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After each usage, your sprayer should be drained and cleaned. It is normally acceptable to leave the product in the sprayer if you intend to spray again later that day or the next day. If you are not going to spray again for at least a day or two, you will need to drain the tank. You should triple-rinse your sprayer after draining the tank. This entails flushing the system three times with fresh water to remove as much chemical residue as possible.